Journal article icon

Journal article

Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies.

Abstract:

BACKGROUND: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), an inflammatory enzyme expressed in atherosclerotic plaques, is a therapeutic target being assessed in trials of vascular disease prevention. We investigated associations of circulating Lp-PLA(2) mass and activity with risk of coronary heart disease, stroke, and mortality under different circumstances. METHODS: With use of individual records from 79 036 participants in 32 prospective studies (yielding 17 722 incident fatal or ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Thompson, A More by this author
Di Angelantonio, E More by this author
Expand authors...
Journal:
Lancet
Volume:
375
Issue:
9725
Pages:
1536-1544
Publication date:
2010-05-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:0b666286-05d3-490c-9d46-4b64d51f3b48
Source identifiers:
92402
Local pid:
pubs:92402

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP