Trace alignment and some of its applications.

Journal article

MOTIVATION: Extra useful information can be extracted from a DNA chromatogram trace, over that contained in the base-called DNA sequence. Many sequencing applications can benefit from examination of these traces. RESULTS: An algorithm, based on dynamic programming, for aligning a DNA chromatogram to a DNA sequence is described and implemented. Its applications to vector clipping, EST alignment and mutation detection are discussed.

Authors: Mott, R

• Publication status: Published
• Journal: Bioinformatics (Oxford, England)
• Volume: 14
• Issue: 1
• Pages: 92-97
• Publication date: 1998-01-01
• DOI: 10.1093/bioinformatics/14.1.92
• EISSN: 1367-4811
• ISSN: 1367-4803
• Language: English
• Keywords: Mutation; Automation; Sequence Alignment; Mathematical Computing; Algorithms; DNA, Complementary; DNA; Sequence Analysis, DNA