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Journal article

Molecular cloning of the cDNA coding for properdin, a positive regulator of the alternative pathway of human complement.

Abstract:

Northern blot analysis indicated that the mRNA for human properdin is approximately 1.5 kb long and that its level in U-937 cells is increased by pretreating the cells with phorbol 12-myristate 13-acetate (PMA). Using a human genomic probe clones coding for human properdin were isolated from a lambda gt10 cDNA library derived from PMA-treated U-937 cells. The sequence of the 1474-bp cDNA insert of the longest clone revealed an open reading fram of 1326 bp coding for the entire 442 amino acids...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830210333

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
European journal of immunology More from this journal
Volume:
21
Issue:
3
Pages:
771-776
Publication date:
1991-03-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Language:
English
Keywords:
Pubs id:
pubs:56496
UUID:
uuid:0b49be9c-a167-45c5-86e3-e7ba47937184
Local pid:
pubs:56496
Source identifiers:
56496
Deposit date:
2012-12-19

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