Journal article
Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis
- Abstract:
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The role of the complement system in viral infections is often complex, with significant implications for pathogenesis and disease. The complement system can form part of the early innate immune response through the binding of glycosylated viral proteins, or through spontaneous activation on viral surfaces. The complement system can also be activated by antibodies in complex with viral antigens. These mechanisms have the potential to inhibit virus interactions with host proteins, mediate opso...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 6.8MB, Terms of use)
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- Publisher copy:
- 10.3389/fimmu.2022.857481
Authors
+ U.S. Food and Drug Administration
More from this funder
- Funder identifier:
- 10.13039/100000038
- Grant:
- HHSF223201510104C
- Publisher:
- Frontiers Media
- Journal:
- Frontiers in Immunology More from this journal
- Volume:
- 13
- Pages:
- 857481-857481
- Article number:
- 857481
- Publication date:
- 2022-04-12
- DOI:
- EISSN:
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1664-3224
- ISSN:
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1664-3224
- Language:
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English
- Keywords:
- Pubs id:
-
1258989
- Local pid:
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pubs:1258989
- Source identifiers:
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W4223651709
- Deposit date:
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2026-04-24
- ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.
Terms of use
- Copyright date:
- 2022
- Licence:
- CC Attribution (CC BY)
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