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No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation.

Abstract:

BACKGROUND: Shipment of pancreata between distant centers is frequently associated with prolonged cold ischemia time (CIT) that leads to poorer outcomes for islet transplantation. Clinical pilot trials have indicated that oxygenation of explanted human pancreata utilizing the two-layer method (TLM) allows the use of marginal donor pancreata for islet transplantation. The present study aimed to clarify whether TLM enhances the ischemic tolerance of human pancreata. METHODS: We analyzed retros...

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Authors


Caballero-Corbalán, J More by this author
Lundgren, T More by this author
Felldin, M More by this author
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Journal:
Transplantation
Volume:
84
Issue:
7
Pages:
864-869
Publication date:
2007-10-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:0b32899c-ba4a-4b69-baa7-00cd43d50cfa
Source identifiers:
266099
Local pid:
pubs:266099

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