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Journal article

GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.

Abstract:

GATA3 has been identified as a master regulator of T helper cells, as well as being important for early thymic progenitors and T-cell commitment. However, Gata3 expression initiates already at the hematopoietic stem cell (HSC) level, implicating a potential role also in the regulation of HSCs. Herein we used a conditional Gata3 knockout strategy in which Gata3 expression was completely deleted from the earliest stage of embryonic hematopoietic development after emergence of HSCs from hemogeni...

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Publication status:
Published

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Journal:
Blood More from this journal
Volume:
118
Issue:
5
Pages:
1291-1293
Publication date:
2011-08-01
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
Language:
English
Keywords:
Pubs id:
pubs:246645
UUID:
uuid:0b16614d-21ea-4186-803f-a29faf0cd029
Local pid:
pubs:246645
Source identifiers:
246645
Deposit date:
2012-12-19

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