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Characterizing vaccine responses using host genomic and transcriptomic analysis.

Abstract:

Vaccines have had a profound influence on human health with no other health intervention rivaling their impact on the morbidity and mortality associated with infectious disease. However, the magnitude and persistence of vaccine immunity varies considerably between individuals, a phenomenon that is not well understood. Recent studies have used contemporary technologies to correlate variation in the genome and transcriptome to immunological measures of vaccine responsiveness. These approaches h...

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Publication status:
Published

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Publisher copy:
10.1093/cid/cit373

Authors


O'Connor, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Biomedical Research Centre
Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
57
Issue:
6
Pages:
860-869
Publication date:
2013-09-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:0b1624d0-3394-48d6-96e8-543ec4a204c1
Source identifiers:
401984
Local pid:
pubs:401984

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