Journal article
Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo.
- Abstract:
-
It is established that the brain monoaminergic systems are among the main targets of several dependence-inducing drugs, including nicotine. In the present study extracellular electrophysiological recordings were performed to investigate the effects of nicotine on dorsal raphe 5-HT neurones. Nicotine, administered systemically (50-400 microg/kg, i.v.) in chloral hydrate-anaesthetised rats, induced a transient inhibition of the majority of 5-HT neurones recorded (38 of 45). The inhibition was r...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Naunyn-Schmiedeberg's archives of pharmacology
- Volume:
- 362
- Issue:
- 1
- Pages:
- 41-45
- Publication date:
- 2000-07-01
- EISSN:
-
1432-1912
- ISSN:
-
0028-1298
- Source identifiers:
-
185183
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:185183
- UUID:
-
uuid:0b11c90c-0148-47b7-bef1-a6a612a6ca7c
- Local pid:
- pubs:185183
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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