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Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes.

Abstract:
A range of heterocycles, namely thiazoles, imidazoles, imidazopyridines, thiazolidines and dimethoxyindoles, have been synthesised directly from alkenes via a two-step ketoidoination/cyclisation protocol. The alkene starting materials are themselves readily accessible using many different and well-established approaches, and allow access to a variety of heterocycles with excellent yields and regioselectivity.
Publication status:
Published

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Publisher copy:
10.1039/c1ob06587d

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Organic and biomolecular chemistry More from this journal
Volume:
10
Issue:
5
Pages:
1093-1101
Publication date:
2012-02-01
DOI:
EISSN:
1477-0539
ISSN:
1477-0520


Language:
English
Keywords:
Pubs id:
pubs:221303
UUID:
uuid:0afa0c75-8f3f-4fb2-99ae-698c7ce9a385
Local pid:
pubs:221303
Source identifiers:
221303
Deposit date:
2012-12-19
ARK identifier:

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