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The progression of replication forks at natural replication barriers in live bacteria

Abstract:

Protein–DNA complexes are one of the principal barriers the replisome encounters during replication. One such barrier is the Tus–ter complex, which is a direction dependent barrier for replication fork progression. The details concerning the dynamics of the replisome when encountering these Tus–ter barriers in the cell are poorly understood. By performing quantitative fluorescence microscopy with microfuidics, we investigate the effect on the replisome when en...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/nar/gkw397

Authors


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Role:
Author
ORCID:
0000-0002-0423-909X
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Name:
Wellcome Trust
Grant:
WT083469
Publisher:
Oxford University Press
Journal:
Nucleic Acids Research More from this journal
Volume:
44
Issue:
13
Pages:
6262-6273
Publication date:
2016-05-10
Acceptance date:
2016-04-28
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
Pmid:
27166373
Language:
English
Keywords:
Pubs id:
pubs:623114
UUID:
uuid:0aefafa9-9837-4908-bf03-808c30eaa6de
Local pid:
pubs:623114
Source identifiers:
623114
Deposit date:
2019-07-03

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