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An improved method for acquiring cerebrovascular reactivity maps.

Abstract:

This study aims to improve the method used to produce cerebrovascular reactivity (CVR) maps by MRI. Previous methods have used a standard boxcar presentation of carbon dioxide (CO(2)). Here this is replaced with a sinusoidally modulated CO(2) stimulus. This allowed the use of Fourier analysis techniques to measure both the amplitude and phase delay of the BOLD CVR response, and hence characterize the arrival sequence of blood to different regions of the brain. This characterization revealed s...

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Publisher copy:
10.1002/mrm.22719

Authors


Blockley, NP More by this author
Driver, ID More by this author
Francis, ST More by this author
Fisher, JA More by this author
Gowland, PA More by this author
Journal:
Magn Reson Med
Volume:
65
Issue:
5
Pages:
1278-1286
Publication date:
2010-12-08
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:0ae7c481-21d7-405b-b55b-dabc14c4cd0d
Source identifiers:
260256
Local pid:
pubs:260256
Language:
English

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