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Journal article

Pain during ice water test distinguishes clinical bladder hypersensitivity from overactivity disorders.

Abstract:

BACKGROUND: The Bladder cooling reflex (BCR) i.e. uninhibited detrusor contractions evoked by intravesical instillation of cold saline, is a segmental reflex believed to be triggered by menthol sensitive cold receptors in the bladder wall, with the afferent signals transmitted by C fibres. The BCR is a neonatal reflex that becomes suppressed by descending signals from higher centres at approximately the time when the child gains full voluntary control of voiding. It re-emerges in adults with...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1471-2490-6-31

Authors


Mukerji, G More by this author
Chessell, IP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Genomics Consortium
Agarwal, SK More by this author
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GlaxoSmithKline UK More from this funder
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
BMC urology Journal website
Volume:
6
Pages:
31
Publication date:
2006
DOI:
EISSN:
1471-2490
ISSN:
1471-2490
URN:
uuid:0ae23dbe-3be2-4737-aa70-a092ee2ab3db
Source identifiers:
33710
Local pid:
pubs:33710

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