Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence.

Lee, EA; Flanagan, KL; Odhiambo, K; Reece, WH; Potter, C; Bailey, R; Marsh, K; Pinder, M; Hill, AV; Plebanski, M

- BibTeX
- EndNote
- RefWorks

Journal article

Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence.

Abstract:: The merozoite surface protein-1 (MSP1) is the most studied malaria blood-stage vaccine candidate. Lymphokines such as interferon gamma (IFN-gamma) and interleukin 4 (IL-4) may mediate blood-stage specific protection. Here we identify Plasmodiumfalciparum MSP1 T-cell epitopes capable of rapid induction of IFN-gamma and/or IL-4 from peripheral blood mononuclear cells of East and West African donors. Both allelic forms of these novel MSP1 T-cell epitopes were stimulatory. An unusually high numbe...
Expand abstract
Collapse abstract

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Lee, E. A., Flanagan, K. L., Odhiambo, K., Reece, W. H., Potter, C., Bailey, R., Marsh, K., Pinder, M., Hill, A. V., & Plebanski, M. (2001). Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence. The American Journal of Tropical Medicine and Hygiene, 64(3-4), 194–203.

MLA Style

Lee, E. A., et al. “Identification of Frequently Recognized Dimorphic T-Cell Epitopes in Plasmodium Falciparum Merozoite Surface Protein-1 in West and East Africans: Lack of Correlation of Immune Recognition and Allelic Prevalence.” The American Journal of Tropical Medicine and Hygiene, vol. 64, no. 3-4, 2001, pp. 194–203.

Chicago Style

Lee, EA, KL Flanagan, K Odhiambo, WH Reece, C Potter, R Bailey, K Marsh, M Pinder, AV Hill, and M Plebanski. 2001. “Identification of Frequently Recognized Dimorphic T-Cell Epitopes in Plasmodium Falciparum Merozoite Surface Protein-1 in West and East Africans: Lack of Correlation of Immune Recognition and Allelic Prevalence.” The American Journal of Tropical Medicine and Hygiene 64 (3-4): 194–203.
Tweet
Print