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Journal article

Recommendations to improve imaging and analysis of brain lesion load and atrophy in longitudinal studies of multiple sclerosis.

Abstract:

Focal lesions and brain atrophy are the most extensively studied aspects of multiple sclerosis (MS), but the image acquisition and analysis techniques used can be further improved, especially those for studying within-patient changes of lesion load and atrophy longitudinally. Improved accuracy and sensitivity will reduce the numbers of patients required to detect a given treatment effect in a trial, and ultimately, will allow reliable characterization of individual patients for personalized t...

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Publication status:
Published

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Publisher copy:
10.1007/s00415-012-6762-5

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of neurology More from this journal
Volume:
260
Issue:
10
Pages:
2458-2471
Publication date:
2013-10-01
DOI:
EISSN:
1432-1459
ISSN:
0340-5354
Language:
English
Keywords:
Pubs id:
pubs:371613
UUID:
uuid:0ace1ae9-a3ac-45c3-9238-4eba7bc52a72
Local pid:
pubs:371613
Source identifiers:
371613
Deposit date:
2013-11-16

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