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Journal article

Validation of a tracer kinetic model for the quantification of 5-HT(2A) receptors in human brain with [(11)C]MDL 100,907.

Abstract:

The positron emission tomography (PET) ligand [(11)C]MDL 100,907 has previously been introduced to image the serotonin 2A (5-HT(2A)) receptor in human brain. The aim of this work was to contribute to the verification of the tracer kinetic modelling in human studies. Five healthy volunteers were scanned twice after intravenous bolus injection of approximately 370 MBq [(11)C]MDL 100,907 using dynamic PET. One scan was performed under baseline condition, the other scan commenced 90 mins after a ...

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Publication status:
Published

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Publisher copy:
10.1038/sj.jcbfm.9600323

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Journal:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Volume:
27
Issue:
1
Pages:
161-172
Publication date:
2007-01-01
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Source identifiers:
139927

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