Journal article
Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry.
- Abstract:
-
The structure of the protein tumour necrosis factor (TNF) was determined from crystals of space group P3(1)21 which contain six copies of the TNF monomer per crystallographic asymmetric unit [Jones, Stuart and Walker (1989). Nature (London), 338, 225-228]. The nature of these crystals (relatively high crystallographic symmetry coupled with multiple copies of the protein in the asymmetric unit) led to some peculiarly challenging problems at several points in the structure determination. In par...
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Bibliographic Details
- Journal:
- Acta Crystallographica Section A: Foundations of Crystallography
- Volume:
- 47
- Publication date:
- 1991-11-01
- DOI:
- ISSN:
-
0108-7673
Item Description
- Language:
- English
- Pubs id:
-
pubs:94064
- UUID:
-
uuid:0a82feb6-dba3-44a2-9499-700092e6a3c8
- Local pid:
- pubs:94064
- Source identifiers:
-
94064
- Deposit date:
- 2013-02-20
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- Copyright date:
- 1991
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