Journal article
Functional MAPT haplotypes: bridging the gap between genotype and neuropathology.
- Abstract:
-
The microtubule-associated protein tau (MAPT) locus has long been associated with sporadic neurodegenerative disease, notably progressive supranuclear palsy and corticobasal degeneration, and more recently with Alzheimer's disease and Parkinson's disease. However, the functional biological mechanisms behind the genetic association have only now started to emerge. The genomic architecture in the region spanning MAPT is highly complex, and includes a approximately 1.8 Mb block of linkage disequ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Neurobiology of disease
- Volume:
- 27
- Issue:
- 1
- Pages:
- 1-10
- Publication date:
- 2007-07-01
- DOI:
- EISSN:
-
1095-953X
- ISSN:
-
0969-9961
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:113361
- UUID:
-
uuid:0a752374-461f-4dfa-9e5b-536a7932ab31
- Local pid:
- pubs:113361
- Source identifiers:
-
113361
- Deposit date:
- 2013-11-17
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- Copyright date:
- 2007
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