Journal article
Strain dependent differences in glucocorticoid-induced bone loss between C57BL/6J and CD-1 mice
- Abstract:
-
We have investigated the effect of long-term glucocorticoid (GC) administration on bone turnover in two frequently used mouse strains; C57BL/6J and CD1, in order to assess the influence of their genetic background on GC-induced osteoporosis (GIO). GIO was induced in 12 weeks old female C57BL/6J and CD1 mice by subcutaneous insertion of long-term release prednisolone or placebo pellets. Biomechanical properties as assessed by three point bent testing revealed that femoral elasticity and streng...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Kennedy Institute of Rheumatology
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 6
- Issue:
- 1
- Article number:
- 36513
- Publication date:
- 2016-11-04
- Acceptance date:
- 2016-09-30
- DOI:
- ISSN:
-
2045-2322
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:656489
- UUID:
-
uuid:0a75109d-7c1d-49d6-ba4e-036f0591adf5
- Local pid:
- pubs:656489
- Deposit date:
- 2016-11-01
Terms of use
- Copyright holder:
- Ersek et al
- Copyright date:
- 2016
- Rights statement:
- Copyright © 2016 The Authors. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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