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Journal article

Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria.

Abstract:

BACKGROUND: Acute kidney injury (AKI) complicating severe Plasmodium falciparum malaria occurs in up to 40% of adult patients. The case fatality rate reaches 75% in the absence of renal replacement therapy (RRT). The precise pathophysiology of AKI in falciparum malaria remains unclear. Histopathology shows acute tubular necrosis with localization of host monocytes and parasitized red blood cells in the microvasculature. This study explored the relationship of plasma soluble urokinase-type pla...

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Publication status:
Published

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Publisher copy:
10.1186/1475-2875-13-91

Authors


Publisher:
BioMed Central
Journal:
Malaria journal More from this journal
Volume:
13
Issue:
1
Pages:
91
Publication date:
2014-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Language:
English
Keywords:
Pubs id:
pubs:458806
UUID:
uuid:0a6afdde-b5dd-4e3a-8f13-3c01bd3d23f3
Local pid:
pubs:458806
Source identifiers:
458806
Deposit date:
2014-06-11

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