Journal article
Training working memory in childhood enhances coupling between fronto-parietal control network and task-related regions
- Abstract:
- Working-memory is a capacity upon which many everyday tasks depend, and which constrains a child’s educational progress. We show that a child’s working-memory can be significantly enhanced by intensive computer-based training, relative to a placebo control intervention, in terms of both standardised assessments of working-memory and performance on a working-memory task performed in a magnetoencephalography (MEG) scanner. Neurophysiologically, we identified significantly increased cross-frequency phase-amplitude coupling in children who completed training. Following training, the coupling between the upper alpha rhythm (at 16 Hz), recorded in superior frontal and parietal cortex, became significantly coupled with high gamma activity (at ~ 90 Hz) in inferior temporal cortex. This altered neural network activity associated with cognitive skill enhancement is consistent with a framework in which slower cortical rhythms enable the dynamic regulation of higher frequency oscillatory activity related to task-related cognitive processes.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.8MB, Terms of use)
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- Publisher copy:
- 10.1523/JNEUROSCI.0101-16.2016
Authors
+ Medical Research Council
More from this funder
- Funding agency for:
- Woolrich, M
- De Ozorio Nobre, A
- Grant:
- MR/K005464/1
- 104571/Z/14/Z
- MC-A060-5PQ41
+ Oxford Biomedical Research Centre
More from this funder
- Funding agency for:
- Woolrich, M
- Grant:
- MR/K005464/1
+ National Institute for Health Research
More from this funder
- Funding agency for:
- Woolrich, M
- Grant:
- MR/K005464/1
+ Wellcome Trust
More from this funder
- Funding agency for:
- Woolrich, M
- De Ozorio Nobre, A
- Grant:
- MR/K005464/1
- 104571/Z/14/Z
- Publisher:
- Society for Neuroscience
- Journal:
- Journal of Neuroscience More from this journal
- Volume:
- 36
- Issue:
- 34
- Pages:
- 9001-9011
- Publication date:
- 2016-08-01
- Acceptance date:
- 2016-07-08
- DOI:
- Pubs id:
-
pubs:635332
- UUID:
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uuid:0a6632ee-5cef-4fa3-8ca8-57525180a2ef
- Local pid:
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pubs:635332
- Source identifiers:
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635332
- Deposit date:
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2016-07-25
- ARK identifier:
Terms of use
- Copyright holder:
- Barnes et al
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Barnes et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International,which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
- Licence:
- CC Attribution (CC BY)
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