Journal article
Assessment of an antibody-in-lymphocyte supernatant assay for the etiological diagnosis of pneumococcal pneumonia in children
- Abstract:
-
New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a potential diagnostic test for pneumococcal pneumonia. We enrolled 348 children with pneumonia admitted to Patan Hospital, Kathmandu, Nepal between December 2015 and September 2016. PBMCs sampled from participants were incubated for 48 h before harves...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- Frontiers Media
- Journal:
- Frontiers in Cellular and Infection Microbiology More from this journal
- Volume:
- 9
- Article number:
- 459
- Publication date:
- 2020-01-17
- Acceptance date:
- 2019-12-16
- DOI:
- EISSN:
-
2235-2988
Item Description
- Language:
- English
- Pubs id:
-
1086347
- Local pid:
- pubs:1086347
- Deposit date:
- 2020-02-11
Terms of use
- Copyright holder:
- Carter et al.
- Copyright date:
- 2020
- Rights statement:
- Copyright © 2020 Carter, Gurung, Jones, Rajkarnikar, Kandasamy, Gurung, Thorson, Gautam, Prajapati, Khadka, Maharjan, Knight, Murdoch, Darton, Voysey, Wahl, O'Brien, Kelly, Ansari, Shah, Ekström, Melin, Pollard, Kelly and Shrestha. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record