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Journal article

Concentrations of IGF-I and IGFBP-3 and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition

Abstract:

Background: Insulin-like growth factors (IGFs) and their binding proteins (BPs) regulate cell differentiation, proliferation and apoptosis, and may have a role in the aetiology of various cancers. Information on their role in pancreatic cancer is limited and was examined here in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition.Methods:Serum concentrations of IGF-I and IGFBP-3 were measured using enzyme-linked immunosorbent assays in 422 cases...

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Publisher copy:
10.1038/bjc.2012.19

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Journal:
British Journal of Cancer
Volume:
106
Issue:
5
Pages:
1004-1010
Publication date:
2012-02-28
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
Source identifiers:
320940
Language:
English
Keywords:
Pubs id:
pubs:320940
UUID:
uuid:0a5d7565-23ca-4fcc-a528-145216ebf369
Local pid:
pubs:320940
Deposit date:
2012-12-19

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