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Perturbation of the BOLD response by a contrast agent and interpretation through a modified balloon model.

Abstract:

This study used an infusion of a paramagnetic contrast agent to perturb intravascular blood susceptibility and investigate its effect on the BOLD hemodynamic response. A three compartment BOLD signal model combined with a modified balloon model was developed to interpret the MR signal. This model incorporated arterial blood volume in order to simulate signal changes resulting from the contrast agent. The BOLD signal model was fitted to the experimental data to test the hypothesis that arteria...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
NeuroImage More from this journal
Volume:
48
Issue:
1
Pages:
84-93
Publication date:
2009-10-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Language:
English
Keywords:
Pubs id:
pubs:268908
UUID:
uuid:0a5a8b31-878b-40ca-9a26-e08f50affc01
Local pid:
pubs:268908
Source identifiers:
268908
Deposit date:
2013-11-17

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