Journal article
Novel therapeutic strategies: targeting epithelial–mesenchymal transition in colorectal cancer
- Abstract:
-
Epithelial–mesenchymal transition (EMT) is a process during which cells lose their epithelial characteristics, for instance apical–basal cell polarity and cell–cell contact, and gain mesenchymal properties, such as increased motility. In colorectal cancer, EMT has an important role in tumour progression, metastasis, and drug resistance. There has been accumulating evidence from preclinical and early clinical studies that show that EMT markers might serve as outcome predictors and potential th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Oncology Journal website
- Volume:
- 22
- Issue:
- 8
- Pages:
- e358-e368
- Publication date:
- 2021-08-01
- Acceptance date:
- 2021-06-08
- DOI:
- EISSN:
-
1474-5488
- ISSN:
-
1470-2045
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1189106
- Local pid:
- pubs:1189106
- Deposit date:
- 2021-08-05
Terms of use
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- 2021
- Rights statement:
- © 2021 Elsevier Ltd. All rights reserved.
- Notes:
-
This is the accepted manuscript version of the article. The final version is available from Elsevier at https://doi.org/10.1016/S1470-2045(21)00343-0
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