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Time-resolved fluorescence imaging for quantitative histochemistry using lanthanide chelates in nanoparticles and conjugated to monoclonal antibodies.

Abstract:

Tissue and cell examinations have a potential to produce extremely valuable information about antigen quantities in samples. Using currently available methods, a truly quantitative analysis is nearly impossible. We have previously shown that immunohistochemical (IHC) detection of prostate-specific antigen and human glandular kallikrein from prostatic tissue, together with time-resolved fluorescence imaging (TRFI), is a suitable method for obtaining quantitative data from biological samples an...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Luminescence : the journal of biological and chemical luminescence
Volume:
15
Issue:
6
Pages:
389-397
Publication date:
2000-01-01
DOI:
EISSN:
1522-7243
ISSN:
1522-7235
URN:
uuid:0a409ae4-e5db-4c03-ada6-c96c694451d0
Source identifiers:
366046
Local pid:
pubs:366046

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