- Abstract:
-
In this review we present recent developments in the analysis of Plasmodium vivax clinical trials and ex vivo drug-susceptibility assays, as well approaches currently being used to identify molecular markers of drug resistance. Clinical trials incorporating the measurement of in vivo drug concentrations and parasite clearance times are needed to detect early signs of resistance. Analysis of P. vivax growth dynamics ex vivo have defined the criteria for acceptable assay thresholds for drug sus...
Expand abstract - Publisher copy:
- 10.1016/j.pt.2012.08.005
-
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- Journal:
- Trends in Parasitology
- Volume:
- 28
- Issue:
- 11
- Pages:
- 522-529
- Publication date:
- 2012-11-05
- DOI:
- EISSN:
-
1471-5007
- ISSN:
-
1471-4922
- URN:
-
uuid:0a39950f-7e06-4288-9b71-b9ea4b95eb74
- Source identifiers:
-
357993
- Local pid:
- pubs:357993
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax
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