Journal article
Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae.
- Abstract:
- Phosphorylation of the Ndc80 kinetochore protein by the Ipl1/Aurora B kinase reduces its microtubule binding activity in vitro. We found that kinetochore-bound Ndc80 is phosphorylated on Ipl1 sites in vivo, but this phosphorylation is not essential. Instead, we show that additional Ipl1 targets contribute to segregation and the spindle checkpoint.
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- Publisher copy:
- 10.1534/genetics.109.109041
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Authors
Bibliographic Details
- Journal:
- Genetics
- Volume:
- 183
- Issue:
- 4
- Pages:
- 1591-1595
- Publication date:
- 2009-12-05
- DOI:
- EISSN:
-
1943-2631
- ISSN:
-
0016-6731
- URN:
-
uuid:0a38b776-e788-4aa1-90bd-4278af063f58
- Source identifiers:
-
228688
- Local pid:
- pubs:228688
Item Description
Terms of use
- Copyright date:
- 2009
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