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Journal article

Smooth muscle gap-junctions allow propagation of intercellular Ca2+ waves and vasoconstriction due to Ca2+ based action potentials in rat mesenteric resistance arteries

Abstract:

The role of vascular gap junctions in the conduction of intercellular Ca2+ and vasoconstriction along small resistance arteries is not entirely understood. Some depolarizing agents trigger conducted vasoconstriction while others only evoke a local depolarization. Here we use a novel technique to investigate the temporal and spatial relationship between intercellular Ca2+ signals generated by smooth muscle action potentials (APs) and vasoconstriction in mesenteric resistance arteries (MA). Pul...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ceca.2018.08.001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
ORCID:
0000-0003-0458-9871
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
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Name:
British Heart Foundation
Grant:
PG/14/58/ 30998
Publisher:
Elsevier
Journal:
Cell Calcium More from this journal
Volume:
75
Issue:
1
Pages:
21-29
Publication date:
2018-08-07
Acceptance date:
2018-08-07
DOI:
Keywords:
Pubs id:
pubs:909512
UUID:
uuid:0a1b6b04-3864-4779-8ad2-7f71018d61b8
Local pid:
pubs:909512
Source identifiers:
909512
Deposit date:
2018-08-23

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