Journal article : Review
The Biosafety Research Road Map: the search for evidence to support practices in the laboratory — SARS-CoV-2
- Abstract:
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Introduction: The SARS-CoV-2 virus emerged as a novel virus and is the causative agent of the COVID-19 pandemic. It spreads readily human-to-human through droplets and aerosols. The Biosafety Research Roadmap aims to support the application of laboratory biological risk management by providing an evidence base for biosafety measures. This involves assessing the current biorisk management evidence base, identifying research and capability gaps, and providing recommendations on how an evidence-based approach can support biosafety and biosecurity, including in low-resource settings.
Methods: A literature search was conducted to identify potential gaps in biosafety and focused on five main sections, including the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies.
Results: There are many knowledge gaps related to biosafety and biosecurity due to the SARS-CoV-2 virus's novelty, including infectious dose between variants, personal protective equipment for personnel handling samples while performing rapid diagnostic tests, and laboratory-acquired infections. Detecting vulnerabilities in the biorisk assessment for each agent is essential to contribute to the improvement and development of laboratory biosafety in local and national systems.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 228.4KB, Terms of use)
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- Publisher copy:
- 10.1089/apb.2022.0039
Authors
- Publisher:
- Mary Ann Liebert, Inc. Publishers
- Journal:
- Applied Biosafety More from this journal
- Volume:
- 28
- Issue:
- 2
- Pages:
- 87-95
- Place of publication:
- United States
- Publication date:
- 2023-06-05
- DOI:
- EISSN:
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2470-1246
- ISSN:
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1535-6760
- Pmid:
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37342515
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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1375744
- Local pid:
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pubs:1375744
- Deposit date:
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2023-09-07
Terms of use
- Copyright holder:
- Blacksell et al
- Copyright date:
- 2023
- Rights statement:
- © Stuart D. Blacksell et al. 2023; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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