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Journal article

A novel method for the purification of HIV-1 p24 protein from hybrid Ty virus-like particles (Ty-VLPs).

Abstract:

The self-assembly properties of a protein encoded by the yeast retrotransposon Ty can be exploited to produce large amounts of recombinant, particulate fusion proteins as hybrid Ty virus-like particles (Ty-VLPs). This system has now been adapted to allow the release of the additional protein by incorporation of a protease cleavage site between the yeast carrier protein and the protein of interest. The purification of the additional protein is facilitated by exploiting the ease with which Ty-V...

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Publication status:
Published

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Authors


Gilmour, JE More by this author
Senior, JM More by this author
Esnouf, MP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
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Journal:
AIDS (London, England)
Volume:
3
Issue:
11
Pages:
717-723
Publication date:
1989-11-05
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:09e4ed4a-b52f-4e3d-baac-3b01e7a89f78
Source identifiers:
15422
Local pid:
pubs:15422

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