Journal article
The candidate TB vaccine, MVA85A, induces highly durable Th1 responses
- Abstract:
-
Background Vaccination against tuberculosis (TB) should provide long-term protective immunity against Mycobacterium tuberculosis (M.tb). The current TB vaccine, Bacille Calmette-Guerin (BCG), protects against disseminated childhood TB, but protection against lung TB in adolescents and adults is variable and mostly poor. One potential reason for the limited durability of protection may be waning of immunity through gradual attrition of BCG-induced T cells. We determined if a MVA85A viral-vecto...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 9
- Issue:
- 2
- Pages:
- ARTN 0087340
- Publication date:
- 2014-02-03
- Acceptance date:
- 2013-12-20
- DOI:
- EISSN:
-
1932-6203
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:09dc7b16-82f9-4e43-8bf9-6a1c6ade4f18
- Local pid:
- pubs:459202
- Source identifiers:
-
459202
- Deposit date:
- 2014-06-16
Terms of use
- Copyright holder:
- Tameris et al
- Copyright date:
- 2014
- Notes:
- Copyright: © 2014 Tameris et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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