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Partition coefficients of indoles and betacarbolines.

Abstract:

Partition coefficients for substituted indoles and betacarbolines were determined in octan-1-ol/water and cyclohexane/water. A comparative study of the results in both systems allows us to discuss the effects played by the different molecular structures, substituents, and aromaticity on the distribution properties of these compounds. In particular, the hydrogen-bond donor (HBD) and hydrogen-bond acceptor (HBA) properties of these solutes were characterized and compared with those of structura...

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Publication status:
Published

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Publisher copy:
10.1021/js960111p
Journal:
Journal of pharmaceutical sciences
Volume:
86
Issue:
1
Pages:
106-109
Publication date:
1997-01-01
DOI:
EISSN:
1520-6017
ISSN:
0022-3549
Language:
English
Keywords:
Pubs id:
pubs:118314
UUID:
uuid:09cf4cd5-d9c0-4bc3-bf2d-cd180dcd8208
Local pid:
pubs:118314
Source identifiers:
118314
Deposit date:
2012-12-19

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