Hippocampal malformations do not necessarily evolve into hippocampal sclerosis.
PURPOSE: Hippocampal malformations have been proposed to underlie or evolve into hippocampal sclerosis, a common cause of refractory partial epilepsy. We report two patients with chronic epilepsy and developmental abnormalities of the hippocampus and cortex. We seek to address, in patients with recurrent convulsive seizures over many decades, whether hippocampal malformations necessarily progress to hippocampal sclerosis. METHODS: The first patient died at age 76 years and had experienced co...Expand abstract
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