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Thesis

Structural studies of integral membrane GPCR accessory proteins

Abstract:

GPCR accessory proteins regulate the strength, efficiency and specificity of signal transfer upon receptor activation. Due to the inherent difficulties of studying membrane proteins in vitro and in vivo, little is known about the structure and topology of these small accessory proteins. Two examples of GPCR accessory proteins are the Melanocortin-2 receptor accessory protein (MRAP) and the Receptor-activity-modifying protein (RAMP) family. MRAP and RAMP1 are the main focu...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
Dr. Jason R. Schnell
Oxford college:
St John's College
Role:
Author

Contributors

Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:09bf7ada-8e58-49f4-a979-bcd0cec95e8b
Local pid:
ora:8165
Deposit date:
2014-03-07

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