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Concurrent mapping of an adenovirus 5/SV40 integration site and the U1 snRNA cluster (RNU1) within 400 kb of the chromosome region 1p36.1.

Abstract:

Previous reports from our group suggested the preferential integration of the viral construct Ad5/SV40 at the short arm subtelomeric region of human chromosome 1. The present study narrows the region of viral integration to site 1p36.1 in a close cytogenetic overlap with the U1 snRNA gene cluster (RNU1) within a distance necessarily smaller than 400 kb as suggested by the size of the YAC in which the two markers were found to coexist. This finding supports the hypothesis that the chromosomal ...

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Publication status:
Published

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Publisher copy:
10.1159/000133793

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Journal:
Cytogenetics and cell genetics
Volume:
67
Issue:
1
Pages:
37-40
Publication date:
1994-01-01
DOI:
EISSN:
1424-859X
ISSN:
0301-0171
Source identifiers:
35803
Language:
English
Keywords:
Pubs id:
pubs:35803
UUID:
uuid:09b43933-61c5-4ab3-abd9-533fcec20bd2
Local pid:
pubs:35803
Deposit date:
2012-12-19

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