Journal article
Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides using a quenched fluorescence assay.
- Abstract:
-
Cell-penetrating peptides (CPPs) have shown great potency for cargo delivery both in vitro and in vivo. Different biologically relevant molecules need to be delivered into appropriate cellular compartments in order to be active, for instance certain drugs/molecules, e.g. antisense oligonucleotides, peptides, and cytotoxic agents require delivery into the cytoplasm. Assessing uptake mechanisms of CPPs can help to develop novel and more potent cellular delivery vectors, especially in cases when...
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Bibliographic Details
- Journal:
- Biochimica et biophysica acta
- Volume:
- 1798
- Issue:
- 3
- Pages:
- 338-343
- Publication date:
- 2010-03-01
- DOI:
- ISSN:
-
0006-3002
- Source identifiers:
-
266894
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:266894
- UUID:
-
uuid:09b3c240-8449-4a60-a836-289f9325e437
- Local pid:
- pubs:266894
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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