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Journal article

Tumor heterogeneity: does it matter?

Abstract:

Introduction: It has long been recognized that tumors are composed of a mosaic of cells and numerous methods have been developed to detect tumor heterogeneity, including in situ hybridization, multi-regional sampling, cytological assays, and whole genome and single cell sequencing. Using these methods, heterogeneity has been observed at the genetic, epigenetic, and phenotypic level in numerous cancers. With the advent of deep sequencing technology, we now appreciate a gr... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/14737140.2019.1667236

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
ORCID:
0000-0002-5450-7590
More by this author
Institution:
University of Oxford
Department:
Oncology
Role:
Author
ORCID:
0000-0002-8838-9406
More by this author
Institution:
University of Oxford
Department:
Oncology
Oxford college:
Worcester College
Role:
Author
ORCID:
0000-0001-9413-0575
More by this author
Institution:
University of Oxford
Department:
Surgical Sciences
Role:
Author
ORCID:
0000-0002-4905-8233
More by this author
Institution:
University of Oxford
Department:
Oncology
Role:
Author
ORCID:
0000-0002-5175-2697
Publisher:
Taylor and Francis
Journal:
Expert Review of Anticancer Therapy More from this journal
Volume:
19
Issue:
10
Pages:
857-867
Publication date:
2019-09-11
Acceptance date:
2019-09-10
DOI:
EISSN:
1744-8328
ISSN:
1473-7140
Pmid:
31510810
Language:
English
Keywords:
Pubs id:
pubs:1054718
UUID:
uuid:09b35e48-9443-41eb-8151-7c500fa471fb
Local pid:
pubs:1054718
Source identifiers:
1054718
Deposit date:
2020-01-15

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