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Efficacy assessment of an MVA vectored Rift Valley Fever vaccine in lambs.

Abstract:

The present study has evaluated the protection conferred by a single subcutaneous dose of a modified vaccinia virus Ankara (MVA) vectored vaccine encoding the Rift Valley Fever virus (RVFV) glycoproteins Gn and Gc in lambs. Three groups of six to seven lambs were immunized as follows: one group received the vaccine (termed rMVA-GnGc), a second group received an MVA vector (vector control) and a third group received saline solution (non-vaccinated control). Fourteen days later, all animals wer...

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Authors


Busquets, N More by this author
Lorenzo, G More by this author
López-Gil, E More by this author
Solanes, D More by this author
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Publisher:
Elsevier
Journal:
Antiviral research
Volume:
108
Issue:
1
Pages:
165-172
Publication date:
2014-08-05
DOI:
EISSN:
1872-9096
ISSN:
0166-3542
URN:
uuid:09a5f5a4-c69e-4f10-b06b-2448f5baf43e
Source identifiers:
469686
Local pid:
pubs:469686

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