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Journal article

Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation.

Abstract:

Bacterial pathogens face stringent challenges to their survival because of the many unpredictable, often precipitate, and dynamic changes that occur in the host environment or in the process of transmission from one host to another. Bacterial adaptation to their hosts involves either a mechanism for sensing and responding to external changes or the selection of variants that arise through mutation. Here we review how bacterial pathogens exploit localized hypermutation, through polymerase slip...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Annual review of genetics More from this journal
Volume:
40
Issue:
1
Pages:
307-333
Publication date:
2006-01-01
DOI:
EISSN:
1545-2948
ISSN:
0066-4197
Language:
English
Keywords:
Pubs id:
pubs:115583
UUID:
uuid:09a50369-d5e5-46af-b044-5c6dc186cca6
Local pid:
pubs:115583
Source identifiers:
115583
Deposit date:
2012-12-19

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