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Mitochondrial genome repositioning during the differentiation of the African trypanosome between life cycle forms is microtubule mediated.

Abstract:

The cell cycle of the African trypanosome requires a precise orchestration of nuclear and mitochondrial genome (kinetoplast) positioning to ensure faithful segregation during division. The controls underlying these events must be subject to modulation, however, as the respective positioning of these organelles changes during the parasite's complex life cycle. We have studied mitochondrial DNA repositioning during differentiation between the trypanosome's bloodstream and procyclic form. We hav...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of cell science
Volume:
108 ( Pt 6)
Pages:
2231-2239
Publication date:
1995-06-01
EISSN:
1477-9137
ISSN:
0021-9533
Language:
English
Keywords:
Pubs id:
pubs:13239
UUID:
uuid:098a2c09-70ee-44f2-b85b-c43cc46cef00
Local pid:
pubs:13239
Source identifiers:
13239
Deposit date:
2012-12-19

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