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Journal article

Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration.

Abstract:

PURPOSE: To investigate the feasibility and to identify sources of experimental variability of quantitative and qualitative fundus autofluorescence (AF) assessment in mice. METHODS: Blue (488 nm) and near-infrared (790 nm) fundus AF imaging was performed in various mouse strains and disease models (129S2, C57Bl/6, Abca4(-/-), C3H-Pde6b(rd1/rd1), Rho(-/-), and BALB/c mice) using a commercially available scanning laser ophthalmoscope. Gray-level analysis was used to explore factors influencing...

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Publication status:
Published

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Publisher copy:
10.1167/iovs.11-8767

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Investigative ophthalmology and visual science More from this journal
Volume:
53
Issue:
2
Pages:
1066-1075
Publication date:
2012-02-29
DOI:
EISSN:
1552-5783
ISSN:
0146-0404
Language:
English
Keywords:
Pubs id:
pubs:221391
UUID:
uuid:0984ada2-f18e-4089-8ff3-c419427cfe81
Local pid:
pubs:221391
Source identifiers:
221391
Deposit date:
2012-12-19

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