Journal article
Mucosal-associated invariant T-cells: new players in anti-bacterial immunity.
- Abstract:
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Mucosal-associated invariant T (MAIT) cells are an innate-like T-cell population involved in anti-bacterial immunity. In human beings, MAIT cells are abundant, comprising ~10% of the CD8(+) T-cell compartment in blood. They are enriched at mucosal sites and are particularly prevalent within the liver. MAIT cells are defined by the expression of a semi-invariant T-cell receptor (Vα7.2-Jα33/12/20) and are restricted by the non-polymorphic, highly evolutionarily conserved MHC class Ib molecule, ...
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- Publisher copy:
- 10.3389/fimmu.2014.00450
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Authors
Bibliographic Details
- Publisher:
- Frontiers Research Foundation
- Journal:
- Frontiers in immunology
- Volume:
- 5
- Issue:
- OCT
- Pages:
- 450
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
1664-3224
- Source identifiers:
-
488368
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:488368
- UUID:
-
uuid:097fecab-7f81-4bbf-8ced-d31062bc22b0
- Local pid:
- pubs:488368
- Deposit date:
- 2014-11-04
Terms of use
- Copyright date:
- 2014
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