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Plasmodium vivax: Isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates

Abstract:

In vitro susceptibility tests provide information on the intrinsic response of Plasmodium vivax to antimalarials, free from confounding factors such as host immunity or relapse. This study examined the utility of radioisotope and PicoGreen assays as alternatives to the traditional microscopic examination for assessing response of P. vivax to antimalarial drugs. There was no significant difference in the mean chloroquine IC50 of P. vivax (n = 40) as determined by the microscopic (33.4 ng/ml), ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Elsevier
Journal:
Experimental Parasitology More from this journal
Volume:
114
Issue:
1
Pages:
34-39
Publication date:
2006-03-20
Acceptance date:
2006-02-07
DOI:
ISSN:
0014-4894
Language:
English
Keywords:
Pubs id:
pubs:358011
UUID:
uuid:097d9cfb-e6e3-4737-9f0e-6ab8b6243280
Local pid:
pubs:358011
Source identifiers:
358011
Deposit date:
2015-11-04

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