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Plasmodium vivax: Isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates

Abstract:

In vitro susceptibility tests provide information on the intrinsic response of Plasmodium vivax to antimalarials, free from confounding factors such as host immunity or relapse. This study examined the utility of radioisotope and PicoGreen assays as alternatives to the traditional microscopic examination for assessing response of P. vivax to antimalarial drugs. There was no significant difference in the mean chloroquine IC50 of P. vivax (n = 40) as determined by the microscopic (33.4 ng/ml), ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Elsevier Publisher's website
Journal:
Experimental Parasitology Journal website
Volume:
114
Pages:
34-39
Publication date:
2006-01-01
DOI:
ISSN:
0014-4894
URN:
uuid:097d9cfb-e6e3-4737-9f0e-6ab8b6243280
Source identifiers:
358011
Local pid:
pubs:358011

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