Journal article icon

Journal article

Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.

Abstract:

There is no reliable means of detecting latent M. tuberculosis infection, and even in patients with active tuberculosis, infection is often unconfirmed. We hypothesized that M. tuberculosis antigen-specific T cells might reliably indicate infection. We enumerated peripheral blood-derived interferon gamma (IFN-gamma)-secreting T cells responding to epitopes from ESAT-6, an antigen that is highly specific for M. tuberculosis complex but absent from BCG, in four groups of individuals. Forty-five...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
American journal of respiratory and critical care medicine More from this journal
Volume:
163
Issue:
4
Pages:
824-828
Publication date:
2001-03-01
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
Language:
English
Keywords:
Pubs id:
pubs:31858
UUID:
uuid:097c4858-e722-4764-a3ae-6cc25e1c7a94
Local pid:
pubs:31858
Source identifiers:
31858
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP