Journal article
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
- Abstract:
-
The cell-surface glycoprotein vascular cell adhesion molecule-1 (VCAM-1; ref. 1) mediates intercellular adhesion by specific binding to the integrin very-late antigen-4 (VLA-4, alpha 4 beta 1; ref. 3). VCAM-1, with the intercellular adhesion molecules ICAM-1, ICAM-2, ICAM-3 and the mucosal vascular addressin MAd-CAM-1, forms an integrin-binding subgroup of the immunoglobulin superfamily. In addition to their clinical relevance in inflammation, these molecules act as cellular receptors for vir...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/373539a0
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Authors
Bibliographic Details
- Journal:
- Nature
- Volume:
- 373
- Issue:
- 6514
- Pages:
- 539-544
- Publication date:
- 1995-02-05
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
- URN:
-
uuid:09765b28-d64d-4481-b329-d20ab84123df
- Source identifiers:
-
25603
- Local pid:
- pubs:25603
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 1995
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