Journal article
Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
- Abstract:
-
HLA-B*27 exerts protective effects in hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections. While the immunological and virological features of HLA-B*27-mediated protection are not fully understood, there is growing evidence that the presentation of specific immunodominant HLA-B*27-restricted CD8+ T-cell epitopes contributes to this phenomenon in both infections. Indeed, protection can be linked to single immunodominant CD8+ T-cell epitopes and functional constraints on e...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Deutsche Forschungsgemeinschaft
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 8
- Issue:
- 11
- Pages:
- e1003042
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:09647e94-ed36-47b9-91c7-1d87800472a8
- Local pid:
- pubs:365459
- Source identifiers:
-
365459
- Deposit date:
- 2013-11-17
Terms of use
- Copyright holder:
- Schmidt et al
- Copyright date:
- 2012
- Notes:
- © 2012 Schmidt et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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