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Immune-complex mediated colitis in rabbits. An experimental model.

Abstract:

An experimental colitis in rabbits is described, following the intravenous injection of preformed immune complexes of human serum albumin (HSA) and anti-HSA into non-sensitised rabbits. Tissue damage was localised to the colon by the Auer technique of inducing local non-specific inflammation, by the rectal instillation of dilute formalin. Formalin alone gave transient changes that reverted to normal within 24 hours. In rabbits given intravenous immune complexes formed in antigen-excess, a sev...

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Publication status:
Published

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Publisher copy:
10.1136/gut.19.3.225
Journal:
Gut More from this journal
Volume:
19
Issue:
3
Pages:
225-232
Publication date:
1978-03-01
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
Language:
English
Keywords:
Pubs id:
pubs:135826
UUID:
uuid:095e3b65-0955-4c4a-9a7a-d07bf526021c
Local pid:
pubs:135826
Source identifiers:
135826
Deposit date:
2012-12-19

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