Journal article icon

Journal article

Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M.

Abstract:

OBJECTIVES: To develop a proteomics approach to study changes in the secreted protein levels of primary human chondrocytes after stimulation by the pro-inflammatory cytokines interleukin-1 and oncostatin M. METHODS: Using both the primary human articular and bovine nasal chondrocyte-conditioned mediums, methods were investigated to enable the separation of proteins by two-dimensional (2D) gel electrophoresis. Differentially regulated proteins were identified using tandem electrospray mass spe...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/rheumatology/kel060

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Expand authors...
Journal:
Rheumatology (Oxford, England)
Volume:
45
Issue:
9
Pages:
1101-1109
Publication date:
2006-09-01
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Source identifiers:
226512

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP