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Journal article

Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes

Abstract:

Illumina sequencing allows rapid, cheap and accurate whole genome bacterial analyses, but short reads (<300 bp) do not usually enable complete genome assembly. Long-read sequencing greatly assists with resolving complex bacterial genomes, particularly when combined with short-read Illumina data (hybrid assembly). However, it is not clear how different long-read sequencing methods affect hybrid assembly accuracy. Relative automation of the assembly process is also crucial to facilitating high-...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1099/mgen.0.000294

Authors


More by this author
Institution:
University of Oxford
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Publisher:
Microbiology Society
Journal:
Microbial Genomics More from this journal
Volume:
5
Issue:
9
Pages:
1-12
Publication date:
2019-09-01
Acceptance date:
2019-08-19
DOI:
EISSN:
2057-5858
Language:
English
Keywords:
Pubs id:
pubs:1046107
UUID:
uuid:094dd989-11e4-41e0-836f-8771ab908327
Local pid:
pubs:1046107
Source identifiers:
1046107
Deposit date:
2019-08-19

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