- Abstract:
-
Suppressor of cytokine signaling (SOCS) proteins are key regulators of CD4(+) T cell differentiation, and in particular, we have recently shown that SOCS2 inhibits the development of Th2 cells and allergic immune responses. Interestingly, transcriptome analyses have identified SOCS2 as being preferentially expressed in both natural regulatory T cells (Tregs) and inducible Tregs (iTregs); however, the role of SOCS2 in Foxp3(+) Treg function or development has not been fully elucidated. In this...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.4049/jimmunol.1201396
-
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- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 190
- Issue:
- 7
- Pages:
- 3235-3245
- Publication date:
- 2013-04-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:0931bc25-af4c-4e7b-bf95-828f7d4b5c2b
- Source identifiers:
-
387830
- Local pid:
- pubs:387830
- Copyright date:
- 2013
Journal article
Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
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